By Joseph Thompson


Pharmaceuticals industries is one of main supplier for medicines. Through the help of expert doctors and chemists they have been able to supply a high quality tablets and fluids that are essential for curing. Those cure must be process in equal amount and number suitable for the need of patients. Any negligence for proper weighing may cultivate to medicine resistance of bacteria. In relative to that, insufficiency and equality may either lead to death or ineffectiveness of medication.

To avoid such accident from happening, owners and medical practitioner always assure to have the strongest and efficient working station by investing to machinery and equipment. Tablet punches and dies are few of its main tool of operation. You could say that this is the root of operation. Hence they assure that this machine responsible for forming and shaping the granules to its exact content and form will be deliver with utmost quality.

Simply put it, this serve as the pillar of every pharmaceutical producer. Through its help, they had been able to curve and put their finish product for consumption. However since the machinery is most use in the operation, they need to put it into constant maintenance. That is only to keep producing quality drugs.

Just thinking about the result is such a pain. In a line of business where trust do matter, it could surely break your reputation once defective drugs had circulated in the market. You might even be held liable under the law for endangering the citizen. Hence to survive in this industry where reputation is always on the line, keep proper maintenance for your tools.

There are many reason why tooling problem occurs. Few of it is the infiltration of moisture, the incorrect particle size of each granules, and other may be due to poor maintenance specifically in regards to its lubricants. Here are few of tablet defects resulted by defective machines.

Binding. This happens due to the poor sticking of die. The pills are subject to easy disintegration or poor shapes. It usually takes place when there are corrosion or abrasion on your dies. You must also learn to lessen the pressure once it occurs. The other option to solve it, is to have your dies polish and keep rust from eating the steel. Also try to check and lessen its tablet size.

Picking. This is necessary for labeling the tablet or drugs by its dosage or logos. When there is roughness in your punch face, that only means that mislabel and misread of the products are present. To avoid it, keep a weak pressure point in your process method.

Molting. It occurs when the color of the drug was not applied thoroughly. Usually it takes place every formulation phase however once you have detected this concern in your lab, keep in mind to change your binder and system solvent. Start again by using smaller granules now.

To resolve such issue, there were standardization established by authorized organization as a compliance for these industries for a safe manufacturing of drugs. Hence manufacturer must be aware about it and apply for the certification. It will be the easiest way to attend trust in the market as well as giving good quality products.




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